Kev tsim cov tshuaj toxicity thiab endocrine cuam tshuam los ntawm triazole fungicides yeej ib txwm yog lub hom phiaj ntawm kev soj ntsuam los ntawm cov koom haum tswj hwm tshuaj tua kab hauv ntiaj teb. Tom qab tshaj tawm cov lus qhia rau kev soj ntsuam ntawm endocrine cuam tshuam ntawm cov tshuaj tua kab thiab tshuaj tua kab mob hauv 2018, European Union lub koom haum tswj hwm, uas yog lub vane ntawm kev lag luam, tau tshaj tawm ib qho kev ntsuam xyuas ntawm endocrine cuam tshuam los ntawm cov tshuaj tua kab tshiab thiab tshuaj tua kab uas tau nkag mus. rov ntsuam xyuas.
Txog rau tam sim no, ntau tus kab mob triazole fungicides, xws li cyproconazole, tau raug txwv los ntawm EU vim muaj peev xwm cuam tshuam txog kev cuam tshuam ntawm endocrine thiab kev ua kom muaj menyuam muaj kuab lom. Tab sis tib lub sijhawm, tus tshiab triazole fungicide cloflufenconazole tau pom zoo los ntawm European Union hauv 2019, rhuav tshem cov kev txwv mus sij hawm ntev tsis muaj cov tshuaj tua kab mob triazole tshiab hauv khw. Prothioconazole, ib qho khoom lag luam nrov triazole, kuj tau ua kom muaj kev vam meej hauv European Union qhov kev rov ntsuam xyuas dua xyoo no. Thawj zaug tau lees paub tias nws tsis muaj qhov cuam tshuam endocrine cuam tshuam. Nws tau npaj tseg tias EFSA thaum kawg yuav lees paub qhov kev soj ntsuam kev pheej hmoo zoo sib xws rau lub Kaum Hlis 30 xyoo no.
Thaum Lub Yim Hli 24, 2023, European Food Safety Authority (EFSA) tau ua tiav qhov kev tshuaj xyuas cov neeg sib tw ntawm metconazole rov txheeb xyuas qhov kev pheej hmoo ntawm kev soj ntsuam daim ntawv tshaj tawm thiab tshaj tawm qhov kev ntsuam xyuas xaus. Cov txiaj ntsig tau pom tias tsis muaj qhov tseem ceeb ntawm kev txhawj xeeb tau raug txheeb xyuas hauv kev ntsuam xyuas tib neeg kev noj qab haus huv, ib puag ncig cov kab mob uas tsis yog lub hom phiaj thiab ib puag ncig cuam tshuam ntawm metconazole. Tib lub sijhawm, metconazole tsis tau pom tias muaj peev xwm cuam tshuam endocrine cuam tshuam rau tib neeg thiab ib puag ncig cov kab mob uas tsis yog lub hom phiaj.
Metconazole feem ntau yog sib xyaw ntawm cis thiab trans isomers, ob qho tib si muaj cov kab mob bactericidal, tab sis daim ntawv cis muaj zog dua li daim ntawv trans. Lub mechanism ntawm kev txiav txim yog tib yam li lwm yam triazole fungicides. Nws yog ib qho inhibitor ntawm C-14 demethylation hauv ergosterol biosynthesis (FRAC: 3). Nws inhibits qhov elongation ntawm pathogenic fungus hyphae thiab tiv thaiv kab mob spores los ntawm invading qoob loo cov ntaub so ntswg.
Metconazole yog qhov dav-spectrum systemic fungicide nrog kev ua haujlwm zoo. Nws yog tsuas yog siv los tiv thaiv thiab tswj Septoria, Fusarium paniculata thiab nplooj xeb hauv cov nplej, dwarf xeb thiab powdery mildew nyob rau hauv barley, thiab crown rust nyob rau hauv oats.
Cov European Union tau lees paub qhov ua tau zoo ntawm metconazole raws li kev ua kom tsis muaj menyuam thiab tswj cov nroj tsuag kev loj hlob, thiab tom qab ntawd ntsuas metconazole los ntawm tib neeg kev noj qab haus huv, ib puag ncig cov kab mob uas tsis yog lub hom phiaj thiab kev cuam tshuam ib puag ncig, thiab cov txiaj ntsig tau raws li hauv qab no:
01. Thaum siv metconazole hauv rapeseed, qhov kev pheej hmoo ntawm cov neeg nyob hauv thiab cov menyuam yaus nyob hauv tsev muaj ntau dua li cov neeg siv.
02. Qhov kwv yees cov seem ntawm cov metabolites ntsig txog metconazole tsis pub tshaj tus nqi siv tshuaj lom neeg.
03. Nyob rau hauv tag nrho cov neeg sawv cev siv, kev pheej hmoo ntawm metconazole rau noog, tsiaj qus tsiaj, muv, tsis yog lub hom phiaj arthropods, earthworms, av microorganisms, non-target terrestrial nroj tsuag thiab dej phwj kho kab mob yog tsawg.
04. Metconazole tsis ua raws li cov txheej txheem qhia txog kev cuam tshuam endocrine hauv tib neeg thiab ib puag ncig cov kab mob uas tsis yog lub hom phiaj (uas yog, nws tsis yog qhov cuam tshuam endocrine).
Tsis tas li ntawd, EFSA tau qhia hauv nws qhov kev txiav txim siab tias tseem muaj qee cov ntaub ntawv sib txawv, uas ua rau muaj kev pheej hmoo ntawm kev ntsuas dej haus thiab cov neeg nyob sib ze tseem tsis tau tiav.
Cov kauj ruam rov qab xyuas
Hauv cov kauj ruam tom ntej, European Commission (EC) yuav tshuaj xyuas cov lus xaus ntawm EFSA thiab daim ntawv tshaj tawm kev ntsuam xyuas rov qab (RAR), thiab yuav xa daim ntawv rov ntsuam xyuas dua thiab cov kev cai lij choj rau cov tswvcuab kom pom zoo kom ncua lossis tsis txuas ntxiv. Kev pom zoo ntawm metconazole. Cov neeg sawv cev ntawm EU cov tswvcuab hauv lub xeev yuav pov npav rau tsab cai lij choj ntawm Pawg Neeg Sawv Cev ntawm Cov Nroj Tsuag, Tsiaj, Khoom Noj thiab Khoom Noj (SCoPAFF).
Tau qhov twg los: AgroPages
